Transcriptomic analysis of the NCI-60 cancer cell lines.
作者： John N. Weinstein , Yves Pommier
DOI: 10.1016/J.CRVI.2003.08.005
关键词: Pharmacogenomics 、 Cancer cell lines 、 Genomics 、 Proteomics 、 Biology 、 Transcriptome 、 Computational biology 、 Human cancer 、 Bioinformatics
摘要: Abstract Pharmacogenomics aims at molecular subsetting of patients for more effective therapy. Transcriptomic profiling the 60 human cancer cell lines (the NCI-60) used by US National Cancer Institute serves that aim because cells have been treated with >100,000 chemical compounds over last 13 years. Patterns potency can be mapped into structures or characteristics cells. We discuss conceptual and experimental aspects profiling, as well a number bioinformatic computer programs we developed biological interpretation profiles. To cite this article: J.N. Weinstein, Y. Pommier, C. R. Biologies 326 (2003).
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