Prevalence of chronic hepatitis B virus infection among patients in the HIV Outpatient Study, 1996-2007.

摘要: Coinfection with hepatitis B virus (HBV) is an important and preventable cause of chronic liver disease among HIV-infected patients. We calculated the prevalence HBV infection annually from 1996 to 2007 by age, gender, race/ethnicity, HIV transmission risk in a multisite observational cohort study Prevalence was as number patients positive HBsAg or detectable DNA divided tested using either one these assays. Among 4467 (59%) for total 7618 active during 1996-2007, median age 38.5 years, 77% were men, 49% white, 35% black, 13% Hispanic, 53% men who had sex (MSM). Overall, 8.4% DNA. Annual 1996-2007 ranged 7.8% 8.6% without statistically significant trend. greater compared women; whites, blacks, persons other race Hispanics; MSM injection drug users high-risk heterosexuals; aged 35-44 years younger older constituted greatest fraction (63-72%) all HBV-infected Outpatient Study (HOPS) over period. Of eligible patients, 5.8%, 23.4%, 31.6% received at least dose vaccine 1996, 2002, 2007, respectively. Despite availability effective two decades long-standing recommendations immunization (with infection) HBV, this has been largely unchanged past decade groups, overall 20 times high national population prevalence.