Effects of airway cooling on tracheal stretch receptors
作者： F.B. Sant'Ambrogio , G. Sant'Ambrogio , O.P. Mathew
DOI: 10.1016/0034-5687(86)90073-3
关键词: Pulmonary stretch receptors 、 Stretch receptor 、 Bronchoconstriction 、 Airway 、 Receptor 、 Respiratory system 、 Respiratory tract 、 Biophysics 、 Breathing 、 Anesthesia 、 Chemistry 、 Physiology 、 Pulmonary and Respiratory Medicine
摘要: Abstract We studied the effect of cold air on tracheal slowly adapting stretch receptors (SAR) in 6 anesthetized, spontaneously breathing dogs. Air at constant flow and two different temperatures was passed through an isolated segment extrathoracic trachea. recorded SAR action potentials, esophageal pressure, pressure temperature. With a reduction temperature ≈10 °C steady state response 30 SARs to distending 1.0 kPa decreased 75% control (P 0.05, n = 8). The 13 sinusoidal oscillations (0.15 kPa) superimposed bias (0.5 reduced ‘peak’ value 71% control; ‘valley’ 67% control), resulting similar change receptor discharge within oscillatory cycle. inhibitory airway cooling may play role cold-induced bronchoconstriction.
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