Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.

作者: Rachel Schiff , James G Christensen , David J Shields , Mothaffar F Rimawi , Matthew J Ellis

DOI: 10.1038/NM.4507

关键词: Text miningReceptorMedicineReceptor tyrosine kinaseTriple-negative breast cancerCancer researchTherapeutic strategyBroad spectrumBreast cancer

摘要: Targeting tyrosine kinase receptors that share the feedback inhibitor PTPN12 leads to broad spectrum therapeutic suppression of triple-negative breast cancer.

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