Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid.

作者: Neil Stahl , Michael Baldwin , Rolf Hecker , Keh-Ming Pan , Alma Burlingame

DOI: 10.1021/BI00136A600

关键词: alpha-MannosidasePhospholipidGene isoformSialic acidGlycanScrapiePrPSc ProteinsBiochemistryBiologyN-Acetylneuraminic acid

摘要: … Furthermore, we show that the PrP GPI contains similar sialylated species. … We therefore carried out a similar experiment with the PrP 27-30 GPI glycan following removal of phosphate …

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