Long-term survival after traumatic brain injury: A population-based analysis

作者: Allen W. Brown , Cynthia L. Leibson , James F. Malec , Patricia K. Perkins , Nancy N. Diehl

DOI: 10.3233/NRE-2004-19105

关键词: PediatricsPoison controlTraumatic brain injuryRelative riskPopulationSurgeryRetrospective cohort studyInjury preventionMedicineMedical recordCase fatality rate

摘要: This population-based retrospective cohort study identified all Olmsted County, MN residents with any diagnosis indicative of potential traumatic brain injury (TBI) during the years 1985 to 2000. The complete community-based medical records a random sample (n =7 ,175) were reviewed confirm and characterize event, determine vital status through 2002. review 1,448 confirmed incident cases; 164 (11%) moderate severe; 1,284 mild. estimated 30-day case fatality rate was 29% for severe cases 0.2% mild cases. Comparison observed mortality over full period follow-up that expected revealed risk ratio (95% CI) 5.29 (4.11-6.71) 1.33 (1.05-1.65) Proportional hazards modeling showed adjusted hazard all-cause relative 5.18 (3.65-7.3) within six months event 1.04 (0.57-1.88) remaining period. analysis indicates persons who experience TBI exhibit small but statistically significant reduction in long-term survival compared general population. is very high, among six-month survivors, similar TBI.

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