Comparison of train-of-four and best clinical assessment during continuous paralysis.
作者： CHARLIE STRANGE , LEIGH VAUGHAN , CHERYL FRANKLIN , JIM JOHNSON
DOI: 10.1164/AJRCCM.156.5.9701079
关键词: Continuous infusion 、 Demographics 、 Paralysis 、 Intensive care 、 Anesthesia 、 Intensive care unit 、 Medicine 、 Neuromuscular monitoring 、 Surgery 、 Chemotherapy 、 Atracurium besilate
摘要: Train-of-four (TOF) monitoring is recommended in published guidelines during use of continuous- infusion neuromuscular blocking agents (NMB) the intensive care unit (ICU). To test that recommendation, dual protocols were established a medical ICU after nursing education. Paralyzed patients received either TOF with goal three twitches or best clinical assessment while receiving atracurium by continuous infusion. Demographics and mean duration paralysis 20 group no different than 16 group. Although most demonstrated tolerance over time, there was difference between groups total mg ( ± SEM) infused (10,460 2,409 versus 9,201 3,237) μ g/kg/min (15.2 1.5 12.0 1.1). The time to recovery (50 10 45 12 min). Two complications occurred group, pulmonary emboli despite prophylaxis an ...
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