作者: Anja Lorch
DOI: 10.1007/978-3-319-17467-9_7
关键词: Clinical Practice 、 Salvage therapy 、 Medicine 、 Recurrent disease 、 Oncology 、 Carboplatin 、 Risk profile 、 In patient 、 Etoposide 、 Chemotherapy 、 Internal medicine
摘要: It was the unsatisfactory results of conventional-dose chemotherapy at time relapse, that led to HDCT being introduced into clinical practice. Even today, combination carboplatin and etoposide (CE) remains mainstay all salvage regimens with HDCT. The use has resulted in long-term remission achieved even patients unfavorable prognoses or multiple relapses. What controversial, however, is role as first-line therapy relapsed highly favorable risk profiles. In order avoid overtreatment, should only be administered specialist centres necessary expertise.