The Ongoing Genetic Adaptation of Streptococcus pneumoniae.
作者： Sandra S. Richter , Daniel M. Musher
DOI: 10.1128/JCM.02283-16
关键词: Biology 、 Clone (cell biology) 、 Virology 、 Streptococcus pneumoniae 、 Serotype 、 Clinical microbiology 、 Conjugate vaccine 、 Genetic adaptation
摘要: ABSTRACT Streptococcus pneumoniae has demonstrated a remarkable ability to adapt during the conjugate vaccine era. The increasing incidence of serotype 35B disease and emergence multidrug-resistant clone reported in this issue Journal Clinical Microbiology (L. Olarte et al., J Clin Microbiol 55:724–734, 2017, https://doi.org/10.1128/JCM.01778-16 ) underscore limitations pneumococcal vaccines that target polysaccharide capsule.
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