Survival differences in European patients with AIDS, 1979-89

摘要: Abstract Objectives : To examine the pattern of survival and factors associated with outcome disease in patients AIDS. Design Inception cohort. Data collected retrospectively from patients9 charts. Setting 52 clinical centres 17 European countries. Subjects 6578 adults diagnosed AIDS 1 January 1979 to 31 December 1989. Main measures Survival after time diagnosis. Results The median diagnosis 20 was months, an estimated at three years 16% (95 confindence interval 15% 17%). Patients southern Europe had a shorter survival, particularly immediately diagnosis, compared central northern (survival one year (95% confidnece interval) 54% (52% 56%) 66% (64% 68%), 65% (63% 66%), respectively. however, similar for all regions. regional differences were less pronounced 1989 earlier years. Improved recent observed variety manifestations used define but significant only Pneumocystis carinii pneumonia. remains unchanged over time. Conclusions seems vary within Europe, being than Europe. magnitude these differences, has declined gradually Short term improved remained equally poor, reflecting fact that underlying infection HIV many complicating diseases essentially uncontrolled.