Prevalence of hypertension by duration and age at exposure to the stroke belt.

摘要: Geographic variation in hypertension is hypothesized as contributing to the stroke belt, an area southeastern United States with high mortality. No study has examined by lifetime exposure belt. This association was studied 19,385 participants REasons for And Racial Differences Stroke (REGARDS) study, a national population-based cohort. Prevalent defined systolic blood pressure ≥140, diastolic ≥90, or use of antihypertensive medications. belt assessed residence at birth, currently, early childhood, adolescence, adulthood, mid-adulthood, and recently. After adjustment age, race, sex, physical activity level, body mass index, smoking, alcohol, education, income, prevalence significantly more strongly related (P < .0001) exposure, adulthood than exposures other times. Birthplace current were independently associated hypertension; however, lifetime, predictive joint model both birthplace residence. That adolescence periods are most recent 20-year period suggests community environmental strategies prevent need start earlier life.