Polymeric nanoparticles for siRNA delivery and gene silencing
作者： Yogesh Patil , Jayanth Panyam
DOI: 10.1016/J.IJPHARM.2008.09.039
关键词: Small interfering RNA 、 Molecular biology 、 Polyethylenimine 、 Biodegradable polymer 、 RNA interference 、 Transfection 、 Chemistry 、 Biophysics 、 Gene silencing 、 Drug carrier 、 PLGA
摘要: … using PLGA alone result in poor encapsulation of siRNA. We … used in gene delivery applications, in the PLGA matrix could … PEI in the PLGA matrix to encapsulate siRNA molecules in …
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