Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

作者: Thomas Merdan , Jindrich Kopec̆ek , Thomas Kissel

DOI: 10.1016/S0169-409X(02)00046-7

关键词: Genetic enhancementTransfectionRibozymeComputational biologyGeneBiochemistryCancerVector (molecular biology)Viral vectorBiologyOligonucleotide

摘要: … has substantially increased our knowledge of the molecular mechanisms of cancer during … Suicide gene therapy offers the perspective to kill cancer cells selectively by using prodrug-…

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