Improved prediction of outcome by contrast echocardiography determined left ventricular remodelling parameters compared to unenhanced echocardiography in patients following acute myocardial infarction.

作者: G. Dwivedi , R. Janardhanan , S. A. Hayat , T. K. Lim , R. Senior

DOI: 10.1093/EJECHOCARD/JEP099

关键词: Ejection fractionProportional hazards modelMedicineInternal medicineMyocardial infarctionProspective cohort studyChi-squared distributionCardiologyReperfusion therapyPredictive value of testsVentricular remodeling

摘要: Aims Contrast echocardiography has been shown to be a more accurate method of assessing left ventricular (LV) remodelling compared with unenhanced after acute myocardial infarction (AMI). However, whether this translated into improved prediction outcome is not known. Methods and results Accordingly, total 89 consecutive patients undergoing contrast 7 10 days AMI reperfusion therapy were followed up for cardiac death (CD) AMI. LV ejection fraction (LVEF), end-systolic volume (ESV), enddiastolic assessed by the two methods independently. Outcome data obtained (mean 46+ 16 months).There 15 (17%) events (eight CDs seven AMIs). LVEF ESV found independent multivariable predictors CD (P ¼ 0.04 P 0.02, respectively) or 0.02 0.01, respectively). Furthermore, provided incremental information 0.004 0.004, 0.03, Conclusion following

参考文章(21)
Pier L Temporelli, Pantaleo Giannuzzi, Gian L Nicolosi, Roberto Latini, Maria G Franzosi, Francesco Gentile, Luigi Tavazzi, Aldo P Maggioni, GISSI-3 Echo Substudy Investigators, Doppler-derived mitral deceleration time as a strong prognostic marker of left ventricular remodeling and survival after acute myocardial infarction: Results of the GISSI-3 Echo substudy Journal of the American College of Cardiology. ,vol. 43, pp. 1646- 1653 ,(2004) , 10.1016/J.JACC.2003.12.036
Gary F. Mitchell, Gervasio A. Lamas, Marc A. Pfeffer, Ventricular Remodeling after Myocardial Infarction Advances in Experimental Medicine and Biology. ,vol. 346, pp. 265- 276 ,(1993) , 10.1007/978-1-4615-2946-0_25
Siri Malm, Sigmund Frigstad, Einar Sagberg, Henrik Larsson, Terje Skjaerpe, Accurate and reproducible measurement of left ventricular volume and ejection fraction by contrast echocardiography Journal of the American College of Cardiology. ,vol. 44, pp. 1030- 1035 ,(2004) , 10.1016/J.JACC.2004.05.068
Leonardo Bolognese, Giampaolo Cerisano, Piergiovanni Buonamici, Alberto Santini, Giovanni M. Santoro, David Antoniucci, Pier Filippo Fazzini, Influence of Infarct-Zone Viability on Left Ventricular Remodeling After Acute Myocardial Infarction Circulation. ,vol. 96, pp. 3353- 3359 ,(1997) , 10.1161/01.CIR.96.10.3353
Leonardo Bolognese, Aleksandar N. Neskovic, Guido Parodi, Giampaolo Cerisano, Piergiovanni Buonamici, Giovanni M. Santoro, David Antoniucci, Left ventricular remodeling after primary coronary angioplasty: patterns of left ventricular dilation and long-term prognostic implications. Circulation. ,vol. 106, pp. 2351- 2357 ,(2002) , 10.1161/01.CIR.0000036014.90197.FA
M St John Sutton, MA Pfeffer, T Plappert, JL Rouleau, LA Moye, GR Dagenais, GA Lamas, M Klein, B Sussex, S Goldman, None, Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation. ,vol. 89, pp. 68- 75 ,(1994) , 10.1161/01.CIR.89.1.68