Coexistence of hepatocellular carcinoma (HCC) and c-Kit negative gastrointestinal stromal tumor (GIST): a case report.
作者： Evangelos Felekouras , Petrou Athanasios , Stefani Vgenopoulou , Ioannis Papaconstantinou , Evangelos Prassas
DOI: 10.1097/SMJ.0B013E31817F027B
关键词: Hepatocellular carcinoma 、 Abdominal cavity 、 Curvatures of the stomach 、 Liver cancer 、 Stromal tumor 、 Cancer 、 Pathology 、 Malignancy 、 Internal medicine 、 GiST 、 Medicine 、 Gastroenterology
摘要: A past history of sporadic solid cancers is disclosed in 10% gastrointestinal stromal tumor (GIST) patients. Simultaneous occurrence with other malignancies encountered 14 to 16%, but the synchronous GIST and hepatocellular carcinoma (HCC) has been reported only once English literature. An 81-year-old male patient presented a preoperatively known HCC, whom small nodular omental adjacent lesser curvature stomach was incidentally discovered. When encountered, thorough intraoperative investigation abdominal cavity currently remains reliable method for detection possible coexisting malignancy.
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sci-hub.st 参考文章(25)
Gina D'amato, Dejka M. Steinert, John C. Mcauliffe, Jonathan C. Trent, Update on the Biology and Therapy of Gastrointestinal Stromal Tumors Cancer Control. ,vol. 12, pp. 44- 56 ,(2005) , 10.1177/107327480501200106
Marek Wronski, Synchronous occurrence of gastrointestinal stromal tumors and other primary gastrointestinal neoplasms World Journal of Gastroenterology. ,vol. 12, pp. 5360- 5362 ,(2006) , 10.3748/WJG.V12.I33.5360
Daniela Tibaudi, Claudia Gramigni, Ulrich Rodeck, Michele Camandona, Graziella Bellone, Ornella Bosco, Tiziana Martone, Giorgio Emanuelli, Carlo Smirne, Nadia Sibona, Anna Carbone, Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential. Cancer Research. ,vol. 61, pp. 2200- 2206 ,(2001)
Maria Debiec-Rychter, Jan Cools, Herlinde Dumez, Raf Sciot, Michel Stul, Nicole Mentens, Hilde Vranckx, Bartosz Wasag, Hans Prenen, Johannes Roesel, Anne Hagemeijer, Allan Van Oosterom, Peter Marynen, Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants Gastroenterology. ,vol. 128, pp. 270- 279 ,(2005) , 10.1053/J.GASTRO.2004.11.020
Michael R. Peterson, Zhe Piao, Noel Weidner, Eunhee S. Yi, Strong PDGFRA positivity is seen in GISTs but not in other intra-abdominal mesenchymal tumors: Immunohistochemical and mutational analyses. Applied Immunohistochemistry & Molecular Morphology. ,vol. 14, pp. 390- 396 ,(2006) , 10.1097/01.PAI.0000203038.33414.A3
Izhar Levy, Paul D Greig, Steven Gallinger, Bernard Langer, Morris Sherman, RPCP BEh, Resection of hepatocellular carcinoma without preoperative tumor biopsy. Annals of Surgery. ,vol. 234, pp. 206- 209 ,(2001) , 10.1097/00000658-200108000-00010
Thomas Tran, Jessica A. Davila, Hashem B. El-Serag, The epidemiology of malignant gastrointestinal stromal tumors: an analysis of 1,458 cases from 1992 to 2000. The American Journal of Gastroenterology. ,vol. 100, pp. 162- 168 ,(2005) , 10.1111/J.1572-0241.2005.40709.X
Jordi Bruix, Morris Sherman, Josep M Llovet, Michel Beaugrand, Riccardo Lencioni, Andrew K Burroughs, Erik Christensen, Luigi Pagliaro, Massimo Colombo, Juan Rodés, None, Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL Conference Journal of Hepatology. ,vol. 35, pp. 421- 430 ,(2001) , 10.1016/S0168-8278(01)00130-1
Evangelos Felekouras, Evangelos Prassas, Michael Kontos, Ioannis Papaconstantinou, Emmanouil Pikoulis, Athanasios Giannopoulos, Christos Tsigris, Michael Tzivras, Chris Bakogiannis, Michael Safioleas, Efstathios Papalambros, Elias Bastounis, Liver Tissue Dissection: Ultrasonic or RFA Energy? World Journal of Surgery. ,vol. 30, pp. 2210- 2216 ,(2006) , 10.1007/S00268-005-0468-0
Guido Torzilli, Masami Minagawa, Tadatoshi Takayama, Kazuto Inoue, Ai-Min Hui, Keiichi Kubota, Kuni Ohtomo, Masatoshi Makuuchi, Accurate preoperative evaluation of liver mass lesions without fine‐needle biopsy Hepatology. ,vol. 30, pp. 889- 893 ,(1999) , 10.1002/HEP.510300411