Azide conjugatable and pH responsive near-infrared fluorescent imaging probes.
作者： Julie Murtagh , Daniel O. Frimannsson , Donal F. O’Shea
DOI: 10.1021/OL902140V
关键词: Azide 、 Conjugate 、 Chemistry 、 Fluorescence intensity 、 Fluorescence-lifetime imaging microscopy 、 Photochemistry 、 Near-infrared spectroscopy 、 Azadipyrromethene 、 Fluorescent imaging 、 Cycloaddition
摘要: The synthesis and photophysical characteristics of a pH responsive near-infrared fluorescence imaging probe is described. A key feature the ability to conjugate by an alkyne−azide cycloaddition reaction its reversible response intensity across physiological range.
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