Metal binding to pyridoxal derivatives. An NMR study of the interaction of Eu(III) with pyridoxal phosphate and pyridoxamine phosphate
作者： B. N. Narasinga Rao , C. Ramakrishnan , P. Balaram
DOI: 10.1007/BF02702885
关键词: Crystallography 、 Phosphate 、 Inorganic chemistry 、 Pyridoxal 、 Slow exchange 、 Moiety 、 Lanthanide 、 Pyridoxamine phosphate 、 Pyridoxal phosphate 、 Chemistry 、 Metal binding 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: The solution conformations of pyridoxal-5’-phosphate and pyridoxamine-5’-phosphate have been investigated using Eu(III) as a nuclear magnetic resonance shift probe. Binding to pyridoxal phosphate results in the formation two complexes, at group \alpha-hydroxy-aldehyde moiety, which are slow exchange on time-scale. lanthanide-induced pseudo contact shifts calculated McConnell-Robertson equation. (J. Chem. Soc. (1950), 22, 1561) good agreement with experimentally observed values for both pyridoxamine lead family closely related conformations.
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sci-hub.se 参考文章(19)
C.D. Barry, C.M. Dobson, D.A. Sweigart, L.E. Ford, R.J.P. Williams, THE STRUCTURE OF A CHOLESTEROL: SHIFT REAGENT COMPLEX IN SOLUTION Nuclear Magnetic Resonance Shift Reagents. pp. 173- 195 ,(1973) , 10.1016/B978-0-12-643050-9.50013-0
Esmond E. Snell, Chemical structure in relation to biological activities of vitamin B6. Vitamins and Hormones Series. ,vol. 16, pp. 77- 125 ,(1958) , 10.1016/S0083-6729(08)60314-3
Max Blum, John W. Thanassi, Metal ion induced reaction specificity in vitamin B6 model systems: The effects of Zn2+ and Cu2+ on the 5-deoxypyridoxal catalyzed reactions of α-phenyl-α-aminomalonic acid Bioorganic Chemistry. ,vol. 6, pp. 31- 41 ,(1977) , 10.1016/0045-2068(77)90005-0
Carlos F. G. C. GERALDES, Robert J. P. WILLIAMS, Nucleotide Torsional Flexibility in Solution and the Use of the Lanthanides as Nuclear‐Magnetic‐Resonance Conformational Probes FEBS Journal. ,vol. 85, pp. 463- 470 ,(1978) , 10.1111/J.1432-1033.1978.TB12261.X
F. Giordano, L. Mazzarella, Crystal and molecular structure of pyridoxamine‐5'‐phosphate hydrochloride Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. ,vol. 27, pp. 128- 134 ,(1971) , 10.1107/S056774087100178X
R. P. Bell, M. H. Rand, K. M. A. Wynne-Jones, Kinetics of the hydration of acetaldehyde Transactions of the Faraday Society. ,vol. 52, pp. 1093- 1102 ,(1956) , 10.1039/TF9565201093
C.D. Barry, J.A. Glasel, R.J.P. Williams, A.V. Xavier, Quantitative determination of conformations of flexible molecules in solution using lanthanide ions as nuclear magnetic resonance probes: Application to adenosine-5′-monophosphate☆ Journal of Molecular Biology. ,vol. 84, pp. 471- 490 ,(1974) , 10.1016/0022-2836(74)90110-7
Takaji Fujiwara, The Crystal and Molecular Structure of Vitamin B6 Derivatives. I. Pyridoxal Phosphate Hydrate and Pyridoxal Phosphate Methyl Hemiacetal Bulletin of the Chemical Society of Japan. ,vol. 46, pp. 863- 871 ,(1973) , 10.1246/BCSJ.46.863
G. A. Bentley, J. M. Waters, T. N. Waters, The crystal structure of (±)-phenylalanine-(pyridoxylidine 5-phosphate)copper(II) Chemical Communications (london). pp. 988- 989 ,(1968) , 10.1039/C19680000988
J. F. Cutfield, D. Hall, T. N. Waters, The crystal structure of copper(II) pyridoxylidene (±)-valine complex Chem. Commun. (London). ,vol. 0, pp. 785- 786 ,(1967) , 10.1039/C19670000785