Extreme diversification driven by parallel events of massive loss of heterozygosity in the hybrid lineage of Candida albicans.

摘要: Candida albicans is the most commonly reported species causing candidiasis. The taxonomic classification of C. and related lineages controversial, with africana (syn. var. africana) stellatoidea stellatoidea) being considered different or varieties depending on authors. Moreover, recent genomic analyses have suggested a shared hybrid origin africana, but potential parental remain unidentified. Although genomes been extensively studied, genome has not sequenced so far. In order to get better understanding evolution clade, assess whether could represent one unknown lineages, we type strain (CBS 1905). This was compared that closely lineage africana. Our results show that, similarly descends from same ancestor as other strains it undergone parallel massive loss heterozygosity.