Dynamics of local neuronal networks: control parameters and state bifurcations in epileptogenesis

作者: Fernando H. Lopes , Jan-Pieter Pijn , Wytse J. Wadman

DOI: 10.1016/S0079-6123(08)60552-X

关键词: EpileptogenesisAttractorNeuroscienceState (computer science)Correlation dimensionDynamics (music)PsychologyControl parameters

摘要: Publisher Summary This chapter discusses aspects of the general behavior local neuronal networks (LNNs) considered as dynamic systems. It focuses on CA1 area rat hippocampus. The main structural and physiological properties elements synaptic circuits are also discussed. dynamics LNNs is systems, i.e. their modes activity under different conditions. basic theoretical concepts non-linear treated to introduce notions such attractors, dimensions, bifurcations chaos. analogies between systems examined, considering changes in correlation dimension Finally, considers how disturbances control parameters—in particular, balance excitatory inhibitory processes (E /I balance) can give rise pathological epilepsy.

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