Gastrointestinal amyloidosis: a case of chronic diarrhoea.

作者: C. Fonnesu , C. Cerquaglia , M. Giovinale , L. Obici , V. Curigliano

DOI:

关键词: Internal medicineAmyloidosisPerforation (oil well)Rare diseaseDiarrheaPathologyMalabsorptionAL amyloidosisDifferential diagnosisGastroenterologyChronic gastritisMedicine

摘要: Amyloidosis is a rare disease caused by extracellular deposits of insoluble fibrillar proteins in various organs and tissues. There are different forms amyloidosis distinguished the type protein fibrils, sites deposition associated conditions. Gastrointestinal involvement common both primary secondary amyloidosis, while isolated gastrointestinal rare. We describe case AL with restrictive cardiomiopathy. A 64 year old woman came to our attention history chronic diarrhoea weight loss, dysphagia, dry mouth, xerophtalmia, gastritis depression. Clinical diagnosis has been difficult because aspecificity symptoms that mimed other more diseases, like gastro-paresis, epigastric discomfort, gastric or duodenal ulcers, perforation, malabsorption, intestinal pseudo-obstruction. an important risk misunderstanding diagnostic delay. Indeed this patient irritable colon syndrome was erroneously established two years before admission hospital. Therefore should be considered among differential diagnoses loss when diseases have excluded.

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