Gastrointestinal amyloid deposits in old age: Report on 110 Consecutive Autopsical Patients and 98 Retrospective Bioptic Specimens
作者： C. Röcken , W. Saeger , R.P. Linke
DOI: 10.1016/S0344-0338(11)80742-9
关键词:
摘要: The prevalence of gastrointestinal amyloid was determined in 110 consecutive autopsy patients aged 85 years and older. Paraffin sections from the esophagus, stomach, small intestine, colon rectum were stained with Congo red inspected polarized light. Amyloid found 38 (36%). Four had generalized amyloidosis remaining 34 revealed more localized varieties amyloid. Immunohistochemical classification a panel antisera directed against five major fibril proteins displayed at least four different types Twenty cases exhibited transthyretin origin, lambda light chain origin one case A-type. Thus far, unclassifiable deposits 18 cases, 16 which strictly subserosal veins. This series compared 98 randomly-selected bioptical tissues according to distribution pattern, sex, frequency various associated diseases.
sci-hub.se 参考文章(40)
P R Greipp, R A Kyle, Amyloidosis (AL). Clinical and Laboratory Features in 229 Cases Mayo Clinic proceedings. ,vol. 58, pp. 665- 683 ,(1983)
R. P. Linke, Amyloid Deposits Derived from Various Proteins — A Hallmark of Old Age Springer, Berlin, Heidelberg. pp. 175- 192 ,(1989) , 10.1007/978-3-642-74996-4_13
Westermark P, Pitkänen P, Cornwell Gg rd, Murdoch W, Amyloid of the seminal vesicles. A distinctive and common localized form of senile amyloidosis. American Journal of Pathology. ,vol. 110, pp. 64- 69 ,(1983)
Reinhold P. Linke, Walter B. J. Nathrath, Manfred Eulitz, Classification of Amyloid Syndromes from Tissue Sections Using Antibodies Against Various Amyloid Fibril Proteins: Report of 142 Cases Springer, Boston, MA. pp. 599- 605 ,(1986) , 10.1007/978-1-4613-2199-6_75
Gerd Mucchiano, Gibbons G. Cornwell Iii, Per Westermark, Senile aortic amyloid. Evidence for two distinct forms of localized deposits. American Journal of Pathology. ,vol. 140, pp. 871- 877 ,(1992)
Jean Pierre Ameryckx, Yves Goffin, M. Hiden, Claude Malmendier, Gibbons Cornwell Iii, E.L. McCrickard, Amyloidosis of the joints: evidence that human hip capsules have a unique predisposition for amyloid of the senile systemic type. Applied pathology. ,vol. 3, pp. 88- 95 ,(1985)
George G. Glenner, Amyloid Deposits and Amyloidosis New England Journal of Medicine. ,vol. 302, pp. 1283- 1292 ,(1980) , 10.1056/NEJM198006053022305
G. G. Cornwell, P. Westermark, R. A. Kyle, P. Pitkanen, L. Benson, B.-O. Olofsson, Senile systemic amyloidosis. American Journal of Pathology. ,vol. 117, pp. 391- 399 ,(1984) , 10.1007/978-1-4613-2199-6_83
Gibbons G. Cornwell, Wendy L. Murdoch, Robert A. Kyle, Per Westermark, Peter Pitkänen, Frequency and distribution of senile cardiovascular amyloid The American Journal of Medicine. ,vol. 75, pp. 618- 623 ,(1983) , 10.1016/0002-9343(83)90443-6
K. Ikeda, H. Murayama, A case of amyloid tumor of the stomach. Endoscopy. ,vol. 10, pp. 54- 58 ,(1978) , 10.1055/S-0028-1098263