Factors Pertaining to Complete Drug-induced Remission of Tumor in Animals and Man

作者: Abraham Goldin

DOI:

关键词: ImmunologyCytarabineDrug toxicityComplete remissionMethotrexateBiologyTumor cell populationDrugLimitingCyclophosphamideInternal medicineOncology

摘要: Summary Complete remission of tumor involves the elimination or control growth cell population and is subject to a balance factors pertaining drug, tumor, host. Among most notable variables which may influence attainment complete are extent action drug on cells, toxicity for host, degree challenge represented by number origin resistance, sequestration pharmacologic immunologic status In therapy, one more host-tumor-drug relationship become limiting, thereby preventing chemotherapeutic agent from exerting sufficient effect at tolerated dosage achieve remission. However, these limiting can be manipulated in favor net increase specificity treatment against examples cited specific approaches worthy further investigation potential value clinic.

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