The early course of bipolar disorder in youth at familial risk.

摘要: Introduction: There has been substantial clinical and research interest in describing the complete natural history of bipolar disorder, related to this significant debate regard validity diagnosis very young children. Given high heritability longitudinal risk studies can provide important information evolution disorder. Methods: A selected review discussion findings from key are presented focusing on relevance for mapping early course illness, addressing referred children implications organization services. Results: To date, there have reported several risks starting with well characterized affected parents, all which support an psychopathology non-specific disorders frank bipolarity. Early childhood antecedents include internalizing sleep typically not behavioural disorders. In majority cases, mood pathology associated morbidity is depressive polarity. None these a single case pre-pubertal mania. Conclusions: These highlight importance considering family diagnostic formulation pediatric patients psychiatric illness. The intervention child psychiatry services discussed.