HLA antigens influence resistance to lung carcinoma.
作者： Paula J. Romano , Mary Bartholomew , Philip J. Smith , Francine Kloszewski , John Stryker
DOI: 10.1016/0198-8859(91)90093-O
关键词: Lung 、 Immunology 、 Lung cancer 、 Respiratory disease 、 Carcinoma 、 Epithelioma 、 Major histocompatibility complex 、 Pathogenesis 、 Human leukocyte antigen 、 Biology
摘要: The concept of genetic factors playing a role in the pathogenesis lung cancer has gained increased attention. present study was undertaken to reexamine question HLA antigen association with carcinoma lung. In 90 patients, significant occurred between HLA-DR7 and resistance cancer, after accounting for smoking status sex. class I antigens were also implicated. These results suggest that major histocompatibility complex loci affect
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