The adipocyte as an endocrine organ in the regulation of metabolic homeostasis.

作者: H. James Harwood

DOI: 10.1016/J.NEUROPHARM.2011.12.010

关键词: Internal medicineEndocrinologyAdipokineMetabolic syndromeAdipocyteBiologyAdiponectinAdipose tissueEnergy homeostasisResistinLeptin

摘要: … of adipokines that interact with central as well as peripheral organs such as the brain, liver, … organ continues to develop, much of the research in this area has focused on adiponectin …

参考文章(296)
Michael A. Cowley, James L. Smart, Marcelo Rubinstein, Marcelo G. Cerdán, Sabrina Diano, Tamas L. Horvath, Roger D. Cone, Malcolm J. Low, Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus Nature. ,vol. 411, pp. 480- 484 ,(2001) , 10.1038/35078085
Anders H. Berg, Terry P. Combs, Xueliang Du, Michael Brownlee, Philipp E. Scherer, The adipocyte-secreted protein Acrp30 enhances hepatic insulin action Nature Medicine. ,vol. 7, pp. 947- 953 ,(2001) , 10.1038/90992
Dongsheng Cai, Minsheng Yuan, Daniel F Frantz, Peter A Melendez, Lone Hansen, Jongsoon Lee, Steven E Shoelson, Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB Nature Medicine. ,vol. 11, pp. 183- 190 ,(2005) , 10.1038/NM1166
Kissebah Ah, Insulin resistance in visceral obesity. International Journal of Obesity. ,vol. 15, pp. 109- 115 ,(1991)
Bruce Wolffenbuttel, A Van Tol, Robin Dullaart, Willem Sluiter, R De Vries, Post-heparin plasma lipoprotein lipase, but not hepatic lipase activity, is related to plasma adiponectin in type 2 diabetic patients and healthy subjects Clinical Laboratory. ,vol. 51, pp. 403- 409 ,(2005)
André Bado, Sandrine Levasseur, Samir Attoub, Stéphanie Kermorgant, Jean-Pierre Laigneau, Marie-Noëlle Bortoluzzi, Laurent Moizo, Thérèse Lehy, Michèle Guerre-Millo, Yannick Le Marchand-Brustel, Miguel. J. M. Lewin, The stomach is a source of leptin Nature. ,vol. 394, pp. 790- 793 ,(1998) , 10.1038/29547
Michael W. Schwartz, Stephen C. Woods, Daniel Porte, Randy J. Seeley, Denis G. Baskin, Central nervous system control of food intake Nature. ,vol. 404, pp. 661- 671 ,(2000) , 10.1038/35007534
M. Cnop, P. J. Havel, K. M. Utzschneider, D. B. Carr, M. K. Sinha, E. J. Boyko, B. M. Retzlaff, R. H. Knopp, J. D. Brunzell, S. E. Kahn, Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia. ,vol. 46, pp. 459- 469 ,(2003) , 10.1007/S00125-003-1074-Z
T. Yamauchi, J. Kamon, H. Waki, Y. Terauchi, N. Kubota, K. Hara, Y. Mori, T. Ide, K. Murakami, N. Tsuboyama-Kasaoka, O. Ezaki, Y. Akanuma, O. Gavrilova, C. Vinson, M.L. Reitman, H. Kagechika, K. Shudo, M. Yoda, Y. Nakano, K. Tobe, R. Nagai, S. Kimura, M. Tomita, P. Froguel, T. Kadowaki, The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity Nature Medicine. ,vol. 7, pp. 941- 946 ,(2001) , 10.1038/90984
Graham M. Lord, Giuseppe Matarese, Jane K. Howard, Richard J. Baker, Stephen R. Bloom, Robert I. Lechler, Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression Nature. ,vol. 394, pp. 897- 901 ,(1998) , 10.1038/29795