Multicentric giant lymph node hyperplasia. A hyperimmune syndrome with a rapidly progressive course.

摘要: A patient who had diffuse lymph node enlargement, fever, skin rashes, anemia and polyclonal hypergammaglobulinemia is described. Histologic examination of nodes taken from different sites (cervical, axillary inguinal) revealed the presence giant hyperplasia. The liver bone marrow showed a moderate lymphocytic plasma cell infiltration. clinical presentation multicentric variety hyperplasia in reported case similar to features usually associated with angio-immunoblastic lymphadenopathy dysproteinemia, indicating that these two disorders may be related affect same organs systems. Alternatively, this histologic reactive progressing rapid declivitous course can considered distinctive separate entity.