[Castleman's disease : a rare differential diagnosis for Heerfordt's syndrome].

摘要: A 50-year-old male patient demonstrated an existing left proptosis for several weeks. The was suffering from physical exhaustion and had lost considerable weight. Furthermore, we observed greatly enlarged parotid submandibular glands on both sides. MRI of the neck showed multiple, sharply circumscribed lesions in major salivary lacrimal as well orbit. Initially suspected Heerfordt's syndrome, a manifestation sarcoidosis, but laboratory diagnosis could not reveal pathological erythrocyte sedimentation rate or increased ACE titer. After exploratory excision right gland, histological examination revealed Castleman's disease. Therefore, initiated immunomodulatory therapy with interleukin-6 receptor antagonists.Castleman's disease is one very rare, benign, lymphoproliferative processes that have tendency to turn malignant. Isolated findings should be completely resected. There are no clear treatment strategies multiple localizations approaches range systemic glucocorticoid chemotherapy treatment. In contrast isolated findings, prognosis multicentric occurrence unfavorable.