LKB1 modulates lung cancer differentiation and metastasis

作者: Hongbin Ji , Matthew R. Ramsey , D. Neil Hayes , Cheng Fan , Kate McNamara

DOI: 10.1038/NATURE06030

关键词: Cancer researchLung cancerCarcinogenesisMetastasisSTK11CDKN2AGermline mutationCarcinomaBiologyCancer

摘要: Germline mutation in serine/threonine kinase 11 (STK11, also called LKB1) results in Peutz–Jeghers syndrome, characterized by intestinal hamartomas and increased incidence of …

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