Effects of midbrain lesions on female sexual behavior in the rat.

作者: J HERNDONJR

DOI: 10.1016/0031-9384(76)90281-X

关键词: MidbrainReflexDopamineMedicineEndocrinologyEstrogenLordosisSerotoninRaphe nucleiNeurochemicalInternal medicine

摘要: Abstract Female sexual behavior was observed in ovariectomized female rats treated with varying doses of estrogen and progesterone, following electrolytic midbrain lesions. Severe deficits receptivity were produced by lesions aimed at the dorsal ventral norepinephrine pathways (DV lesions) intended to destroy meso-limbic (A-10) dopamine-producing cells. Significant but less profound impairments seen serotonin-producing raphe nucleus or nigro-striatal dopamine Systemically administered d-amphetamine found increase severely impaired A-10 DV animals. The may result from damage structures involved sensory-motor hormonal mediation lordosis reflex, disruption a neurochemical system control lordosis.

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