Isorhynchophylline Ameliorates Cognitive Impairment via Modulating Amyloid Pathology, Tau Hyperphosphorylation and Neuroinflammation: Studies in a Transgenic Mouse Model of Alzheimer's Disease
作者： Hui-Qin Li , Siu-Po Ip , Qiu-Ju Yuan , Guo-Qing Zheng , Karl K.W. Tsim
DOI: 10.1016/J.BBI.2019.08.194
关键词: Neuroinflammation 、 Internal medicine 、 Amyloid precursor protein 、 Chemistry 、 Genetically modified mouse 、 Endocrinology 、 Microglia 、 Hippocampus 、 Cerebral cortex 、 Insulin-degrading enzyme 、 Radial arm maze
摘要: Isorhynchophylline (IRN) has been demonstrated to have distinct anti-Alzheimer’s disease (AD) activity in several animal models of AD. In this study, we aimed at evaluating the …
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