Suan-Zao-Ren Decoction ameliorates synaptic plasticity through inhibition of the Aβ deposition and JAK2/STAT3 signaling pathway in AD model of APP/PS1 transgenic mice

作者: Ping Wang , He-Yuan Shi , Ai-Hua Tan , Yong-Gui Wu , Li-Ling He

DOI: 10.1186/S13020-021-00425-2

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摘要: … All herbal ingredients were confirmed by the Department of Chinese Medicine pharmacy at the Hubei University of Chinese Medicine. Referred to Gao’s report, the stock solution of …

参考文章(58)
Sha Li, Lin Kang, Yizhou Zhang, Baofeng Feng, Juan Du, Huixian Cui, Detecting the presence of hippocampus membrane androgen receptors in male SAMP8 mice and their induced synaptic plasticity Molecular and Cellular Endocrinology. ,vol. 414, pp. 82- 90 ,(2015) , 10.1016/J.MCE.2015.07.005
Minho Moon, Jin Gyu Choi, Dong Woo Nam, Hyun-Seok Hong, Young-Ju Choi, Myung Sook Oh, Inhee Mook-Jung, Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-β1-42 oligomer-injected mice. Journal of Alzheimer's Disease. ,vol. 23, pp. 147- 159 ,(2011) , 10.3233/JAD-2010-101263
T Chiba, M Yamada, J Sasabe, K Terashita, M Shimoda, M Matsuoka, S Aiso, Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons. Molecular Psychiatry. ,vol. 14, pp. 206- 222 ,(2009) , 10.1038/MP.2008.105
Zhi Liu, Xu Zhao, Bing Liu, Ai-jing Liu, Huan Li, Xin Mao, Bo Wu, Kai-shun Bi, Ying Jia, Jujuboside A, a neuroprotective agent from semen Ziziphi Spinosae ameliorates behavioral disorders of the dementia mouse model induced by Aβ1–42 European Journal of Pharmacology. ,vol. 738, pp. 206- 213 ,(2014) , 10.1016/J.EJPHAR.2014.05.041
John C Breitner, Laura D Baker, Thomas J Montine, Curtis L Meinert, Constantine G Lyketsos, Karen H Ashe, Jason Brandt, Suzanne Craft, Denis E Evans, Robert C Green, M Saleem Ismail, Barbara K Martin, Michael J Mullan, Marwan Sabbagh, Pierre N Tariot, ADAPT Research Group, Extended results of the Alzheimer's disease anti-inflammatory prevention trial. Alzheimers & Dementia. ,vol. 7, pp. 402- 411 ,(2011) , 10.1016/J.JALZ.2010.12.014
Sangram S. Sisodia, Alzheimer's disease: perspectives for the new millennium. Journal of Clinical Investigation. ,vol. 104, pp. 1169- 1170 ,(1999) , 10.1172/JCI8508
HB Guo, YF Cheng, JG Wu, CM Wang, HT Wang, C Zhang, ZK Qiu, JP Xu, None, Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation Neuroscience. ,vol. 290, pp. 530- 542 ,(2015) , 10.1016/J.NEUROSCIENCE.2015.01.058
Zuo-hui Zhang, Lin-jie Yu, Xin-chen Hui, Zheng-zheng Wu, Kai-lin Yin, Hui Yang, Yun Xu, Hydroxy-safflor yellow A attenuates Aβ1-42-induced inflammation by modulating the JAK2/STAT3/NF-κB pathway Brain Research. ,vol. 1563, pp. 72- 80 ,(2014) , 10.1016/J.BRAINRES.2014.03.036
Eun Ju Jeong, Hee Kyoung Lee, Ki Yong Lee, Byung Ju Jeon, Dae Hyun Kim, Jin-Ho Park, Joo-Ho Song, Jungmoo Huh, Jong-Hwan Lee, Sang Hyun Sung, The effects of lignan-riched extract of Shisandra chinensis on amyloid-β-induced cognitive impairment and neurotoxicity in the cortex and hippocampus of mouse. Journal of Ethnopharmacology. ,vol. 146, pp. 347- 354 ,(2013) , 10.1016/J.JEP.2013.01.003
A. Auffret, V. Gautheron, M. Repici, R. Kraftsik, H. T. J. Mount, J. Mariani, C. Rovira, Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease The Journal of Neuroscience. ,vol. 29, pp. 10144- 10152 ,(2009) , 10.1523/JNEUROSCI.1856-09.2009