Antimicrobial resistance pattern of Gram-positive bacteria during three consecutive years at the nephrology ward of a tertiary referral hospital in Shiraz, Southwest Iran

摘要: Objective: The aim of the present study was to determine pattern antimicrobial resistance Gram-positive bacteria during three consecutive years at nephrology ward Namazi Hospital in Shiraz, Southwest Iran. Methods: During a 3-year period from 2013 2015, data all biological samples hospitalized patients adult were sent central laboratory for identification microorganisms and subsequently, their susceptibility testing by Kirby–Bauer disc diffusion method analyzed retrospective manner. Findings: Coagulase-negative Staphylococci (CONS) (38.5%), Staphylococcus aureus(25.4%), Enterococcus spp. (23.8%) most common isolated samples. All isolates within 3 resistant oxacillin. rate vancomycin-resistant enterococci (VRE) increased 40.63% 72.73% 2015. rates aminoglycosides above 85%. frequencies oxacillin-resistant S. aureus (ORSA) 2013, 2014, 2015 95.24%, 80.95%, 36.36%, respectively. Two out 11 (6.67%) vancomycin. More than 90% CONS sensitive vancomycin period. frequency gentamicin-resistant ranged 40% 57.14%. Conclusion: ORSA, VRE, aminoglycoside-resistant as well our clinical setting considerably high concerning. These may be due failure or lack infection control activities selection pressure.