作者: Yanghee Woo , Carolyn E. Behrendt , Garrick Trapp , Jae Geun Hyun , Tamas Gonda
DOI: 10.1002/JSO.24622
关键词: Medicine 、 Metaplasia 、 Family history 、 Cancer 、 Gastritis 、 Internal medicine 、 Former Smoker 、 Risk assessment 、 Gastroenterology 、 Intestinal metaplasia 、 Helicobacter pylori
摘要: Background Gastric cancer (GC) is the leading cause of death among Korean Americans. Prevention and early detection improved by screening. Methods Between September 2013 March 2015, ethnic Koreans age 40 or older without history symptoms GC upper endoscopy (UE) during previous 3 years were enrolled. Participants offered screening with risk assessment followed UE biopsies. Results Risk was provided to 146 participants (age 55.6 ± 8.3 years; 52.1% female; 92.5% uninsured), whom 99 (67.8%) returned for UE. Undergoing independently associated family (OR 12.33, 95% CI:1.52-100.17), being a former smoker (6.68,1.42-31.32), Hp-negative status (0.25,0.11-0.57). Among recipients, half (49.5%) had intestinal metaplasia (IM) only (n = 24), Hp (n = 12), both (n = 13). No case found. Adjusted age, IM male sex (2.89,1.12-7.42), current (2.90,0.99-8.51), unmarried (single divorced) (4.23,1.23-14.56). Conclusions High prevalence factors gastric carcinogenesis including infection exists in Americans who underwent endoscopic screening. Acceptance informed personal factors. These findings support need improve access KAs.