Helicobacter pylori Eradication in the Prevention of Gastric Cancer: Are More Trials Needed?

摘要: The incidence of gastric cancer has decreased in much the world, but remains second leading cause death globally, and burden is growing many countries East Asia Latin America. Chronic infection with Helicobacter pylori dominant cancer, two recent randomized trials showed that H. eradication significantly risk. Population screening treating individuals for also appears to be cost-effective. Nevertheless, current clinical guidelines differ as whether asymptomatic adults should screened treated pylori, no have yet implemented programs. Some this inaction may reflect lingering doubts about effectiveness preventing there uncertainty possible risks mass antibiotic treatment its impact on gut flora. Appropriately designed studies will help address these issues hasten implementation population-wide prevention