EGFR-TKI down-regulates PD-L1 in EGFR mutant NSCLC through inhibiting NF-κB

作者: Kailong Lin , Jianan Cheng , Tao Yang , Yongsheng Li , Bo Zhu

DOI: 10.1016/J.BBRC.2015.05.030

关键词: GefitinibLung cancerTargeted therapyWild typeEpidermal growth factor receptorPD-L1ImmunotherapyCancer researchMedicineCTLA-4

摘要: … Collectively, these data indicate that NF-κB is required for the elevated PD-L1 expression in … expression of PD-L1 by gefitinib was dependent on NF-κB, we examined the NF-κB activity …

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