Gefitinib Induces Apoptosis in the EGFRL858R Non–Small-Cell Lung Cancer Cell Line H3255

作者: Sean Tracy , Toru Mukohara , Mark Hansen , Matthew Meyerson , Bruce E. Johnson

DOI: 10.1158/0008-5472.CAN-04-1905

关键词: EGFR inhibitorsEpidermal growth factor receptorProtein kinase BPathologyCancer researchAdenocarcinomaLung cancerApoptosisTyrosine kinaseGefitinibMedicine

摘要: Somatic mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) have recently been described in patients with non–small-cell lung cancer (NSCLC) who …

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