El papel de la dieta materna en la programación metabólica y conductual: revisión de los mecanismos biológicos implicados

摘要: Over the last few years, a considerable amount of studies have focused on effect undernutrition and overnutrition during critical periods offspring development their risk developing metabolic diseases later in life. Additionally, inadequate maternal diets been involved malprogramming brain functions some behaviours. Several mechanisms associated with process such as epigenetics modifications, excessive oxidative stress or hypothalamic alterations. This evidence supports idea that nutritional prevention strategies must be considered for early stages include preconceptional period. studying could particularly useful search efficient therapies against malprogramming.