Influence of tidal volume on ventilation inhomogeneity assessed by electrical impedance tomography during controlled mechanical ventilation.

摘要: Abstract The global inhomogeneity (GI) index is a parameter of ventilation that can be calculated from images tidal distribution obtained by electrical impedance tomography (EIT). It has been suggested the GI may useful for individual adjustment positive end-expiratory pressure (PEEP) and guidance ventilator therapy. aim present work was to assess influence volume (VT) on values. EIT data 9 patients with acute respiratory distress syndrome ventilated low high VT 5   ±   1 (mean  ±  SD) 9   ±   1 ml kg(-1) predicted body weight at level PEEP (PEEPhigh, PEEPlow) were analyzed. PEEPhigh PEEPlow set 2 cmH2O above 5 cmH2O below lower inflection point quasi-static loop, respectively. identified 8.1   ±   1.4 cmH2O, resulting in 10.1   ±   1.4 3.1   ±   1.4 cmH2O. At PEEPhigh, we found no significant trend when compared (0.49   ±   0.15 versus 0.44   ±   0.09, p = 0.13). PEEPlow, significantly higher (0.66   ±   0.19 0.59   ±   0.17, 0.01). When comparing levels, both VT. We conclude lead index, especially settings. This should taken into account using