Inheritance of Resistance to Deltamethrin in Aedes aegypti (Diptera: Culicidae) From Cuba.

摘要: The development of pyrethroid resistance in Aedes aegypti (L) (Diptera: Culicidae) is a serious concern because major A. control programs are predominantly based on use during epidemic disease outbreaks. Research about the genetic basis for and how it transmitted among mosquito populations needed. objective this study was to determine deltamethrin inherited Cuban aegypti-resistant reference strain. Here, field population from Santiago de Cuba (SAN-F14), subjected 14 generations selection high level (91.25×), used prepare reciprocal F1 backcross progeny with insecticide-susceptible Rockefeller Bioassays larvae were performed according World Health Organization guidelines. activities metabolic enzymes assayed through synergist biochemical tests. null hypothesis parallelism test between two probit regression lines (susceptible females × resistant males vice versa) not rejected at 5% significance (P = 0.42), indicating autosomal inheritance. LC50 response both progenies elevated but less than highly SAN-F14 DLC values 0.91 0.87, respectively, suggesting that strain as an incompletely dominant trait, involving least factors, which implies faster lost product effectiveness. Metabolic including esterases cytochrome P-450 monooxygenases glutathione-S-transferases involved larvae.