Sample size determination: Extended tables for the multiplicative model and bioequivalence ranges of 0.9 to 1.11 and 0.7 to 1.43.
作者： D Hauschke , V W Steinijans , E Diletti
DOI:
关键词: Normal distribution 、 Multiplicative model 、 Applied mathematics 、 Equivalence (measure theory) 、 Mathematics 、 Statistics 、 Sample size determination 、 Logarithm 、 Bioequivalence
摘要: For the two-period crossover design and a multiplicative model (logarithmic normal distribution) decision procedure of choice is based on inclusion shortest 90%-confidence interval for ratio expected medians test reference in equivalence range. This rule equivalent to two one-sided tests procedure. Sample sizes power latter have been given by Diletti et al. [1991] an range 0.8 1.25. Corresponding tables tighter 0.9 1.11 as well wider 0.7 1.43 are this amendment.
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