Ultrastructural Study Across the Leprosy Spectrum

作者: V. Vicente Ortega , F. Martíanez Díaaz , G. Ortuńto Pacheco , F. Calderóan Rubiales

DOI: 10.3109/01913129409023213

关键词: LeprosyUltrastructureGiant cellEndoplasmic reticulumCytoplasmVacuoleBiologyBacilliBorderline LepromatousPathology

摘要: We have carried out a systematic ultrastructural study of the bacilli, cell-mediated response in host, and dermal microvasculature lepromatous (LL), borderline (BL), tuberculoid (BT) types active leprosy (eight cases). In least resistance (LL BL), macrophages with large cytoplasmic processes were observed; addition, numerous peripheral vacuoles found BL. Mast cells abundant vascular alterations constant. BT showed more regular outlines multivacuolated cytoplasms plentiful rough endoplasmic reticulum. Giant scarce. Bacilli, both isolated globi, contained within appeared constantly endothelial Schwann LL Conversely, they singly, infrequently cells, not at all cells. Forms process destruction or degradation common than intact forms, which symmetric outline membrane could be seen clearly.

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