Enhanced catalyzed reporter deposition
作者： Kevin Aaron Roth , Mark Norman Bobrow , Karl Edwin Adler
DOI:
关键词: Substituent 、 Organic compound 、 Stereochemistry 、 Polymer chemistry 、 Heteroatom 、 Substrate (chemistry) 、 Reagent 、 Conjugate 、 Alkyl 、 Phenol 、 Chemistry
摘要: A method for enhancing the conversion of a phenol substrate to product by peroxidase enzyme comprises steps reacting conjugate comprising detectably labeled with in presence an reagent, reagent inorganic salt, organic compound having formula (I) wherein when X is B(OH)2, Y I, or OH, halogen, Q-R Q linear branched 1-12 heteroatom alkyl heteroatoms are selected from C, N, O, and S, bonds connecting chain single double, any carbon atom optionally includes substituent -OH, -COOH, -NH2, -SH, R -CH3; mixtures salt compound. (II) -CH2OH, n 1-8.
lens.org 参考文章(16)
Mark N. Bobrow, Krista J. Shaughnessy, Gerald J. Litt, Catalyzed reporter deposition, a novel method of signal amplification. II. Application to membrane immunoassays. Journal of Immunological Methods. ,vol. 137, pp. 103- 112 ,(1991) , 10.1016/0022-1759(91)90399-Z
Robert Alan Pranis, Richard Kao, Frank Arthur Blocki, Walter C. Mahoney, Luminescent analyses with enhanced storage stability ,(1986)
Kevin Aaron Roth, Mark Norman Bobrow, A method of permanent fluorescent assay ,(2000)
Richard Calvin Ebersole, Mark Norman Bobrow, Gerald Joseph Litt, John Richard Moran, Catalyzed reporter deposition ,(1990)
Thomas Joseph Erickson, Mark Norman Bobrow, Compounds and method for synthesizing sulfoindocyanine dyes ,(1997)
Thomas Patterson Whitehead, Gary Harold Gregory Henry Thorpe, Larry Jan Kricka, Enhanced luminescent or luminometric assay ,(1984)
Robert L. Stout, Catalyzed colorimetric and fluorometric substrates for peroxidase enzyme determinations ,(1983)
A. S. H. De Jong, M. Van Kessel-Van Vark, A. K. Raap, Sensitivity of various visualization methods for peroxidase and alkaline phosphatase activity in immunoenzyme histochemistry The Histochemical Journal. ,vol. 17, pp. 1119- 1130 ,(1985) , 10.1007/BF01002537
A.V. Rama Rao, K. Laxma Reddy, A. Srinivasa Rao, Studies directed towards the total synthesis of vancomycin : Formation of biphenyl ether by macrocyclisation Tetrahedron Letters. ,vol. 35, pp. 8465- 8468 ,(1994) , 10.1016/S0040-4039(00)74434-0
Mark N. Bobrow, Thomas D. Harris, Krista J. Shaughnessy, Gerald J. Litt, Catalyzed reporter deposition, a novel method of signal amplification application to immunoassays Journal of Immunological Methods. ,vol. 125, pp. 279- 285 ,(1989) , 10.1016/0022-1759(89)90104-X