Response to Fluid Boluses in the Fluid and Catheter Treatment Trial
作者： Matthew R Lammi , Brianne Aiello , Gregory T Burg , Tayyab Rehman , Ivor S Douglas
关键词: Hemodynamics 、 Cardiac index 、 ARDS 、 Pulmonary artery catheter 、 Central venous pressure 、 Shock (circulatory) 、 Mean arterial pressure 、 Pulmonary wedge pressure 、 Medicine 、 Anesthesia
摘要: BACKGROUND Recent emphasis has been placed on methods to predict fluid responsiveness, but the usefulness of using boluses increase cardiac index in critically ill patients with ineffective circulation or oliguria remains unclear. METHODS This retrospective analysis investigated hemodynamic responses ARDS Network Fluid and Catheter Treatment Trial (FACTT) who were given protocol-based boluses. responsiveness was defined as ≥ 15% after a 15 mL/kg bolus. RESULTS A convenience sample 127 enrolled FACTT analyzed for physiologic 569 protocolized crystalloid albumin shock, low urine output (UOP), pulmonary artery occlusion pressure (PAOP). There significant increases mean central venous (9.9 ± 4.5 11.1 4.8 mm Hg, P = .59). no differences 90-day survival, need hemodialysis, return unassisted breathing between responders nonresponders. CONCLUSIONS In this cohort previously resuscitated, rate low, only led small changes.
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