Long-term outcome of endoscopic dual pancreatobiliary sphincterotomy in patients with manometry-documented sphincter of Oddi dysfunction and normal pancreatogram.

摘要: Background: For patients with sphincter of Oddi dysfunction and abnormal pancreatic basal pressure, additional sphincterotomy has been recommended. The outcome endoscopic dual pancreatobiliary sphincteretomy in manometry-documented was evaluated. Methods: An ERCP database searched for data entered from January 1995 to November 2000 on who met the following parameters: manometry both ducts, pressure at least 1 (≥40 mm Hg), no evidence chronic pancreatitis, sphincterotomy. Patients were offered reintervention by repeat if clinical symptoms not improved. frequency analyzed according ducts previous cholecystectomy, type, method. Results: A total 313 followed a mean 43.1 months (median, 41.0 months; interquartile range: 29.8–60.0 months). Immediate postendoscopic complications occurred 15% patients. Reintervention required 24.6% median follow-up (interquartile range) 8.0 (5.5–22.5) months. similar irrespective or Of type III dysfunction, 28.3% underwent compared 20.4% combined types I II ( p =0.105). When biliary alone historical control our unit, had lower rate comparable those ducts. Conclusion: Endoscopic is useful dysfunction. Prospective randomized trials versus based findings are progress.