The potential of liposomes with carbonic anhydrase IX to deliver anticancer ingredients to cancer cells in vivo.
作者： Huei Ng , Aiping Lu , Ge Lin , Ling Qin , Zhijun Yang
DOI: 10.3390/IJMS16010230
关键词: In vivo 、 Drug delivery 、 Chemistry 、 Targeted drug delivery 、 Pharmacology 、 Carbonic Anhydrase IX 、 Liposome 、 Nanocarriers 、 Cancer 、 Cancer cell
摘要: Drug delivery nanocarriers, especially targeted drug by liposomes are emerging as a class of therapeutics for cancer. Early research results suggest that liposomal enhanced efficacy, while simultaneously reducing side effects, owing to properties such more localization in tumors and active cellular uptake. Here, we highlight the features immunoliposomes distinguish them from previous anticancer therapies, describe how these provide potential therapeutic effects not achievable with other modalities. While large number studies has been published, emphasis here is placed on carbonic anhydrase IX (CA-IX) conjugated likely open new chapter system using deliver ingredients cancer cells vivo.
mdpi.com
core.ac.uk
sci-hub.se 参考文章(176)
Ruey-Long Hong, Yun-Long Tseng, Phase I and pharmacokinetic study of a stable, polyethylene-glycolated liposomal doxorubicin in patients with solid tumors: the relation between pharmacokinetic property and toxicity. Cancer. ,vol. 91, pp. 1826- 1833 ,(2001) , 10.1002/1097-0142(20010501)91:9<1826::AID-CNCR1203>3.0.CO;2-J
Juha Saarnio, Seppo Parkkila, Anna-Kaisa Parkkila, Abdul Waheed, Matthew C. Casey, Xiao Yan Zhou, Silvia Pastoreková, Jaromir Pastorek, Tuomo Karttunen, Kari Haukipuro, Matti I. Kairaluoma, William S. Sly, Immunohistochemistry of Carbonic Anhydrase Isozyme IX (MN/CA IX) in Human Gut Reveals Polarized Expression in the Epithelial Cells with the Highest Proliferative Capacity Journal of Histochemistry and Cytochemistry. ,vol. 46, pp. 497- 504 ,(1998) , 10.1177/002215549804600409
José L Arias, Liposomes in drug delivery: a patent review (2007 - present). Expert Opinion on Therapeutic Patents. ,vol. 23, pp. 1399- 1414 ,(2013) , 10.1517/13543776.2013.828035
A.D. Bangham, M.M. Standish, G. Weissmann, The action of steroids and streptolysin S on the permeability of phospholipid structures to cations. Journal of Molecular Biology. ,vol. 13, pp. 253- ,(1965) , 10.1016/S0022-2836(65)80094-8
Vasileios Askoxylakis, Volker Ehemann, Shoaib Rana, Susanne Krämer, Nuh N. Rahbari, Jürgen Debus, Uwe Haberkorn, Binding of the Phage Display Derived Peptide CaIX-P1 on Human Colorectal Carcinoma Cells Correlates with the Expression of Carbonic Anhydrase IX International Journal of Molecular Sciences. ,vol. 13, pp. 13030- 13048 ,(2012) , 10.3390/IJMS131013030
Thierry Soldati, Manfred Schliwa, Powering membrane traffic in endocytosis and recycling Nature Reviews Molecular Cell Biology. ,vol. 7, pp. 897- 908 ,(2006) , 10.1038/NRM2060
Peter M Kanter, Gary M Klaich, Gary A Bullard, John M King, Marcel B Bally, Lawrence D Mayer, Liposome encapsulated vincristine: preclinical toxicologic and pharmacologic comparison with free vincristine and empty liposomes in mice, rats and dogs. Anti-Cancer Drugs. ,vol. 5, pp. 579- 590 ,(1994) , 10.1097/00001813-199410000-00010
Donatella Paolino, Mariano Licciardi, Christian Celia, Gaetano Giammona, Massimo Fresta, Gennara Cavallaro, Folate-targeted supramolecular vesicular aggregates as a new frontier for effective anticancer treatment in in vivo model. European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 82, pp. 94- 102 ,(2012) , 10.1016/J.EJPB.2012.06.001
P Caliceti, Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates. Advanced Drug Delivery Reviews. ,vol. 55, pp. 1261- 1277 ,(2003) , 10.1016/S0169-409X(03)00108-X
R. W. HORNE, A. D. BANGHAM, V. P. WHITTAKER, NEGATIVELY STAINED LIPOPROTEIN MEMBRANES. Nature. ,vol. 200, pp. 1340- 1340 ,(1963) , 10.1038/2001340A0