Zn(ii) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and -9 independent apoptose induction
作者： Nenad R. Filipović , Snežana Bjelogrlić , Aleksandar Marinković , Tatjana Ž. Verbić , Ilija N. Cvijetić
DOI: 10.1039/C5RA19849F
关键词: Apoptosis 、 Human serum albumin 、 Stereochemistry 、 Perchlorate 、 Intercalation (chemistry) 、 Ligand (biochemistry) 、 Quenching (fluorescence) 、 DNA 、 Chemistry 、 Caspase 8 、 General chemistry 、 General Chemical Engineering
摘要: A new Zn(ii)-based complex shows a concentration-dependent apoptotic response in highly resistant pancreatic adenocarcinoma cells with extensive activation of caspase-8 and -9.
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