Cyto-histological correlations in primary, recurrent and metastatic rhabdomyosarcoma: the institut Curie's experience.

摘要: To determine diagnostic cytomorphologic features of rhabdomyosarcoma (RMS) on fine-needle aspiration (FNA) material, the cytologic material and corresponding histologic slides 180 tumors obtained from 109 patients were reviewed. Fifty eight (32.2%) primary, 34 (18.9%) recurrent, 88 (48.9%) metastatic. A review original cytology reports revealed that 176 (97.8%) either diagnosed accurately or as round cell sarcoma, while 3 (1.7%) reported suspicious. In one case (0.5%), was unsatisfactory. No false negative samples seen. When FNA morphology correlated with different histological subtypes, alveolar subtype RMSs more cellular than nonalveolar ones (91.4% vs. 64.9%). Similarly, compared exhibited rhabdomyoblastic cells (77.1% 52.7%), structures (67.6% 10.8%), giant, multinucleated (22.9% 6.7%), mitotic figures (57.1% 18.9%), cyto-nuclear atypia 43.2%). Inversely, spindle-shaped frequently seen in versus (37.8% 20.9%). Diagn. Cytopathol. 2007;35:482–487. © 2007 Wiley-Liss, Inc.