Mutagenicity testing, in bacterial test systems, of some constituents of tobacco.

作者: M. Riebe , K. Westphal , P. Fortnagel

DOI: 10.1016/0165-1218(82)90163-X

关键词: Ames testChemistryPyrrolidineMutagenicity TestMyosmineNicotineDNA damageAnatabineMicrobiologyEscherichia coli

摘要: Abstract Of 12 tobacco constituents tested, none showed mutagenic activity in the Ames test. The substances pyrrolidine, nicotine, anatabine, myosmine, 2,3′-dipyridyle and nicotyrine induced repairable DNA damage a test with Escherichia coli pol A + / − .

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