Severe acute pulmonary haemorrhage and haemoptysis in ten dogs following eastern brown snake (Pseudonaja textilis) envenomation: Clinical signs, treatment and outcomes

摘要: Abstract This report describes a series of ten cases fulminant pulmonary haemorrhage in dogs following envenomation by the eastern brown snake (Pseudonaja textilis) south Queensland, Australia. All were presented for veterinary treatment during 2011–2018 at specialist emergency centre. Each case received prompt antivenom and supportive care. Pulmonary was diagnosed based on clinical examination; overt haemoptysis; thoracic radiographic demonstration diffuse alveolar pattern; and, presence venom induced consumptive coagulopathy. The median elapsed time from hospital admission to onset haemoptysis 2 h (range 0–18 h). In 80% (8/10) endotracheal intubation required, whilst 20% (2/10) successfully treated with mask oxygen supplementation alone, 40% (4/10) mechanical ventilation; but only 25% (1/4) these survived discharge. Fresh frozen canine plasma administered 70% (7/10) 43% (3/7) survived. Of total number treatment, 30% (3/10) discharge, 60% (6/10) euthanised due poor prognosis 10% (1/10) died cardiac arrest. Initial serum antigen levels retrospectively measured samples specific sandwich ELISA two 154 ng/mL (survived) 3607 (euthanised); no free detected post-antivenom. Dogs that discharged without apparent complications. is an uncommon event P. textilis has not been described similarly envenomed humans. highlights potential fatal envenomation.