ENTEROCOLITIS AND COLON CANCER IN INTERLEUKIN-10 : DEFICIENT MICE ARE ASSOCIATED WITH ABERRANT CYTOKINE PRODUCTION AND CD4+ TH1-LIKE RESPONSES

作者: D. D.J. Berg , D.J. , Davidson , N.J. , Kühn

DOI: 10.1172/JCI118861

关键词: Interleukin 10Colorectal cancerMedicineImmunologySmall intestineEnterocolitisInflammationPathologyCecumInterferon gammaCytokine

摘要: We have characterized the progressive stages of chronic intestinal inflammation that develops spontaneously in specific pathogen-free (SPF) mice with a targeted disruption in the IL-10 …

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